Peyton Manning threw 4 touchdown passes to lead the Colts over the Jaguars 28-25 for the 2nd time this season. Peyton Manning made 20 of 29 passes for 288 yards and had 4 touchdowns in a match for the 1st time this year. Manning connected twice with Clark and once with both Lawton and Wayne to cap off scoring drives. Reggie Wayne finished with 8 catches for 158 yards, while Dallas Clark had 7 receptions for 60 yards as the Indianapolis Colts improved to 10-2 for the season and remained perfect (4-0) in the AFC’s South Division.

Gray is not annoyed by all the talk about how the Jacksonville Jaguars could sink because of the player’s inexperience. The rarely used quarterback is 1-0 after beating the Buccaneers 24-23 in his 1st National Football League start Sunday. That’s all that matters to Gray and Jacksonville (5-2) as they try to stay afloat while David Garrard is recovering from a sprained left ankle expected to keep Quinn in the lineup for up to 4 weeks. Quinn Gray overthrew a large number of open receivers and only passed for a hundred yards. He had a crucial thirteen-yard completion to Wilford on third-and-six, then finished an 8-play, 53-yard drive with an eight-yard TD throw to Jones to put the Jaguars ahead for good.